
Penelitian ini bertujuan untuk mengetahui jarak titik-titik referensi, kedalaman kurva Spee berdasarkan jenis kelamin dan sisi mandibula, serta bentuk kurva Spee pada mahasiswa Fakultas Kedokteran Gigi Universitas Sumatera Utara (FKG USU) usia 18-24 tahun dengan oklusi kelas I Angle.


Kurva Spee dipengaruhi oleh variasi pola wajah, perkembangan sistem neuromuskular, periode gigi-geligi dan waktu erupsi gigi. orellana seed coat’s has been shown to have no effect on the liver function, so it is safe as food colorant (Sains Medika, 3(1):69-77).Pendahuluan: Kurva Spee adalah garis oklusi dalam arah sagital yang diperoleh dari insisal insisivus sentralis hingga distal marginal ridge gigi molar kedua dan berfungsi dalam pergerakan mandibula dan biomekanik mastikasi. Results : Kruskal Wallis test results shows a not significant difference SGOT and SGPT level among the groups (p > 0.05), thus consumption of colorant powder of bixin, norbixin, and the crude extract with various concentrations did not affect the SGOT and SGPT.Ĭonclusion : Colorant powder isolated from B. Powdered colorant solution at the concentration of 0% (control), 1%, 5%, and 10% were orally administered using gavage as much as 1 ml a day for 30 days.

A total of 60 male mice were divided into 10 treatment groups. Food Colorant Powder was made from bixin, norbixin, and crude extract pigment isolated from B. orellana seed coat’s at various concentrations.ĭesign and Methods : The research is an experimental research with Factorial Design with 2 factors. This study conducted to determine the levels of SGOT and SGPT blood serum of mice (Mus musculus) Balb/C after administration of colorant powder pigment of B. Consumption of pigment from kesumba keling (Bixa orellana) was assumed to cause adverse effects on heart as an important organ in detoxification or inactivation of drugs or other toxic compounds.

Background : There has been an effort to explore pigment from kesumba keling’s (Bixa orellana) seed coats for a source of natural food colorant.
